منابع مشابه
Technique for lymphocyte transformation.
Current techniques for lymphocyte transformation are evaluated and criticised. A simple technique, designed to meet these criticisms, is described in detail, with particular reference to lymphocyte separation and scoring methods.
متن کاملAerobic glycolysis and lymphocyte transformation.
1. The role of enhanced aerobic glycolysis in the transformation of rat thymocytes by concanavalin A has been investigated. Concanavalin A addition doubled [U-(14)C]glucose uptake by rat thymocytes over 3h and caused an equivalent increased incorporation into protein, lipids and RNA. A disproportionately large percentage of the extra glucose taken up was converted into lactate, but concanavalin...
متن کاملLymphocyte transformation in malnourished children.
Selimeyer, E., Bhettay, E., Truswell, A. S., Meyers, 0. L., and Hansen, J. D. L. (1972). Archives of Disease in Childhood, 47, 429. Lymphocyte transformation in malnourished children. In vitro lymphocyte stimulation with phytohaemagglutinin gave subnormal transformation values in children with proteincalorie malnutrition. It is suggested that impaired cell-mediated immunity may be one important...
متن کاملMitogen-induced lymphocyte transformation after general anaesthesia.
There is evidence that general anaesthesia interferes with the immune response in man (Bruce and Wingard, 1971). It may affect postoperative infections, anaphylaxis, response to organ transplantation and tumour growth. It has been speculated that there is a relationship between this immunosuppression and the development of postoperative hepatitis (Bruce and Wingard, 1971). Anaesthetists appear ...
متن کاملVancomycin Hypersensitivity Diagnosed by Lymphocyte Blast Transformation
A 15-year-old male admitted for Pott's puffy tumor developed recurrent episodes of fever, diffuse morbilliform rash, eosinophilia, and tubulointerstitial nephritis while on multiple antibiotics. Lymphocyte blast transformation (LBT), a method of detecting cellular immune response by measuring levels of interferon-γ (IFN-γ), was used to diagnose vancomycin hypersensitivity and guide antibiotic s...
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ژورنال
عنوان ژورنال: American Review of Respiratory Disease
سال: 1972
ISSN: 0003-0805
DOI: 10.1164/arrd.1972.106.2.194